单侧隐睾史男性精液质量及精子形态学的研究

Investigation of semen quality and sperm morphology in Men with a history of unilateral cryptorchidism

目的研究单侧隐睾史男性精液质量及精子形态学状况。方法 26例幼年曾确诊为单侧隐睾并行睾丸固定术的男性,成年后分别检测精子密度、精子活率、精子活力及进行精子形态学分析。对照组为无隐睾病史的体检正常男性30例。结果两组男性的精子密度、精子活率无明显差异(P>0.05),而单侧隐睾史男性精子活力低于对照组(t=4.43,P<0.01),精子畸形率较高(t=4.29,P<0.01)。精子畸形的类型以头部缺陷为主。结论单侧隐睾史男性成年后精液质量下降。幼年阶段及早手术治疗有利于成年后的精子发生。

Objective： To investigate semen quality and sperm morphology in men with a history of unilateral cryptorchidism in childhood.Methods：Semen sample were obtained from 26 men with a history of unilateral cryptorchidism in childhood and 30 nomal controls.Semen analysis and sperm morphology were performed using standard procedures.Results：There was no significant difference in sperm density and motility between the two groups,but majority of men with the history had lower sperm activity（t=4.43,P0.01）and higher percentage of abnormal sperm morphology（t=4.29,P0.01）than controls.The head defects were observed as the predominant type of sperm malformation.Conclusion：Semen quality and sperm morphology in men with a history of unilateral cryptorchidism in childhood were poorer than that of normal man.Early surgical management of the undescended testicle can preserve fertility of adulthood.