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piggyBac转座子应用研究进展 被引量：7

Advance in Application of piggyBac Transposon
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摘要 piggyBac转座子是来源于鳞翅目昆虫粉纹夜蛾(Trichoplusia ni)的DNA型转座子。目前piggyBac转座子已成为在昆虫中应用最广泛的转座子之一。近年来国内外研究者更将其应用领域拓宽到了鱼类,寄生虫和哺乳动物等转基因研究中。随着对piggyBac转座子功能和分布的深入认识,piggyBac转座子将更多应用于基因功能研究,基因治疗,转座子介导的细胞系基因诱变及基因工程蛋白表达等基础研究和应用研究中。 The piggyBac element is a kind of DNA transposon which derivated from Trichoplusia ni,and it has been one of the transposons mostly used in insects so far.Researchers have enlarged its application areas in transgenic aspects on Pisces,parasite and mammalian.As the cognition of its function and disposition profounds,the piggyBac transposon will be applied in more areas such as gene function and therapy,transposon mutagenesis of cell line,engineered protein expression and so on.
作者 杨欢欢 魏峰 刘全
机构地区 中国人民解放军军事医学科学院军事兽医研究所 吉林农业大学生命科学学院
出处 《动物医学进展》 CSCD 北大核心 2010年第12期91-94,共4页 Progress In Veterinary Medicine
基金 国家自然科学基金项目(30972178) 国家科技支撑计划项目(2010BAD04B01)
关键词 PIGGYBAC转座子 转基因 应用 piggyBac transposon transgene application
分类号 Q782 [生物学—分子生物学]
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参考文献23

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二级参考文献33

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动物医学进展
2010年 第12期

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