突发性耳聋患儿血液流变学指标检测及分析

Determination and Analysis of Hemorrheological Parameters in Children with Idiopathic Deafness

目的观察突发性耳聋患儿的血液流变学指标变化。方法对32例突发性耳聋患儿和40例正常小儿进行血液流变学检测,比较二者指标变化。结果突发耳聋患儿全血粘度30 s较对照组明显升高(P<0.05);全血粘度5s、1 s,全血低切相对粘度,全血还原粘度以及血浆粘度100 s均较对照组显著升高(P<0.01);红细胞变形指数(TK)相对正常患儿降低(P<0.05)。血沉、红细胞压积、血沉方程K值、全血高切还原粘度及相对粘度与对照组比较差异无统计学意义。结论血液流变学指标的检测对小儿突发耳聋的诊断有一定的临床价值。

Objective To observe the changes of hemorrheological parameters in children with idiopathic deafness. Methods Thirteen hemorrheological parameters were determined in 32 children with idiopathi deafness（ID） and 40 healthy children,and the determination results of the two groups were compared. Results The whole blood viscidity in 30s in children with ID was significantly higher than that in healthy children（P〈0.05）.The whole blood viscidity in 5s,1s,plasma viscidity in 100s,low shear relativity viscidity and reduced viscidity in whole blood of ID children were significantly higher than those in healthy children（P〈0.01）.The Tk in whole blood of ID children was lower than that in healthy children（P〈0.05）.There was no statistically significant difference in the whole blood viscidity in 200s,ESR,the K factor,high shear relativity and reduced viscidity of whole blood between ID children and healthy children. Conclusions There is clinical significance in determination of the changes of hemorrheological parameters for diagnosing idiopathic deafness in children.