姜黄素多孔淀粉微球对蟾蜍黏膜纤毛转运能力的影响

Effects of Curcumin Starch Microspheres on Mucociliary Movement of Toad Venon Maxilla

目的:研究姜黄素多孔淀粉微球对蟾蜍黏膜纤毛转运能力的影响。方法:以在体蟾蜍上颚黏膜纤毛为模型,以聚酰胺颗粒为指示物,观察其在纤毛表面持续运动的速率。结果:姜黄素混悬液对蟾蜍上颚黏膜纤毛的运动有明显的抑制,而姜黄素多孔淀粉微球对纤毛转运能力没有明显影响。结论:姜黄素多孔淀粉微球能显著降低姜黄素对纤毛转运能力的抑制。

OBJECTIVE： To investigate the effect of the curcumin starch microspheres on the movement of cilia in toad venon maxilla. METHODS： Using mucociliary of toad venon maxilla as model, the translation rates of polyamide granule were observed. RESULTS： The movements of the cilia were inhibited by the curcumin suspension significantly while not by curcumin starch microspheres. CONCLUSION： The curcumin starch microspheres can significantly reduce the mucociliary movement.