山西省隰县大仓鼠对杀鼠灵的抗药性研究

Resistance of Tscherskia triton to warfarin in Shanxi Xixian

目的检测山西省隰县大仓鼠对第一代抗凝血灭鼠剂杀鼠灵的抗药性。方法实验室配制0.05%杀鼠灵小米毒饵,采用6d无选择摄毒法。结果杀鼠灵对25只大仓鼠毒杀率为84.0%,死亡鼠平均食毒剂量为149.20mg/kg,平均致死时间为5.29d;存活鼠平均食毒剂量为167.13mg/kg;抗性发生率为16.00%。结论大仓鼠对第一代抗凝血灭鼠剂杀鼠灵已经形成了抗药性个体,但根据判定标准的要求尚未产生抗药性种群。

Objective To identify the resistance of the great long-tailed hamster （Tscherskia triton） to the 1st generation anticoagulant rodenticide, warfarin, in Xixian, Shanxi province. Methods Non-selective feeding test was conducted. The rodents were given baits containing 0.05% warfarin for 6 consecutive days. Results The mortality of 25 T. triton was 84.0% after exposure, and the average amount of bait intake was 149.20 mg/kg. The average lethal time was 5.29 d. The average intake among survivals was 167.13 mg/kg, and the resistance rate was 16.0%. Conclusion T. triton individuals resistant to the 1st generation anticoagulant rodenticides existed, though resistant population has not yet developed according to the relevant criteria.