滕州市乳腺癌危险因素的病例对照研究

Case-control Study on Risk Factors of Breast Cancer in Tengzhou

目的调查滕州市女性乳腺癌危险因素,为确定高危人群、制定干预对策与措施提供依据。方法选取滕州市2007年1月-2009年5月期间,经病理学证实的102例乳腺癌患者,进行1:1的病例对照研究,用SPSS12.0软件进行单因素和多因素logistic分析。结果经多因素非条件Logistic回归分析,最终进入模型的因素为乳腺良性疾病史、不良性格、流产史、月经初潮年龄及哺乳史,其OR值分别为3.411、2.479、1.751、0.725和0.282。结论乳腺良性疾病史、不良性格、流产史、月经初潮年龄小的人群易患乳腺癌,母乳喂养是乳腺癌发病的保护性因素。

Objective To investigate the risk factors of female breast cancer Tengzhou City and to determine high-risk groups, formulating strategies and measures to provide evidence. Methods The 102 cases confirmed by pathological method among breast cancer patients form Jan 2007 to May 2009 in Tengzhou were selected ,1：1 matched case-control was conducted ,the data was analyzed with univariate and multivariate logistic by SPSS12.0 software . Results The non-conditional logistic regression analysis identified five major relevant factors,such as ：history of benign breast disease, bad character, abortion, age of menarcbe and nursing history＇, the OR values were 3.411,2.479,1.751,0.725 and 0.282. Conclusion The risk factors of developing breast cancer were the history of benign breast disease, bad character, abortion, younger menarche, breast feeding is protective factors for breast cancer incidence .