急性缺血性脑卒中患者尿微量白蛋白检测的临床意义

Clinical significance of microalbuminuria determination in patients with acute ischemic cerebral apoplexy

目的:分析急性缺血性脑卒中患者尿微量白蛋白的水平,探索其临床应用价值。方法:比较急性缺血性脑卒中患者与对照组的尿微量白蛋白的水平差异,进一步探讨与神经系统功能缺损评分(斯堪的那维亚评分,SSS评分)的相关性。结果:急性缺血性脑卒中患者尿微量白蛋白阳性率明显升高,与对照组比较,差异有显著意义;与SSS评分之间呈负相关性。结论:尿微量白蛋白是急性缺血性脑卒中发生、发展及预后的独立预测指标,在其防治中具有重要临床意义。

Objective：To evaluate the clinical significance of determining the microalbuminuria concentration in patients with cerebral apoplexy from acute ischemia.Methods：The level of urinary microalbuminuria was determined by immunoturbidimetry for the difference between the acute ischemic stroke patients and control subjects as well as their correlation in terms of neurological deficit score by Scandivian Stroke Scale（SSS）.Results：Positive microalbuminuria was found in 59.7% of acute ischemic stroke patients and in 24% of the controls,which was significantly different and negatively correlated with the SSS score（P0.05;r=-0.93）.Conclusion：The concentration of microalbuminuria may serve as an important indicator to predicate the onset and estimate the development and prognosis of this disease,and has clinical implications in this disease prevention and diagnosis.