64层CT冠状动脉成像技术和冠状动脉造影对冠状动脉疾病诊断的对照研究

Comparison between 64-slice computed tomography coronary angiography and coronary angiography for detecting coronary artery disease

目的比较64层计算机断层摄影扫描冠状动脉成像技术(64-slice computed tomography coronaryangiography,64-SCTCA)和冠状动脉造影(coronary artery angiography,CAG)在冠状动脉粥样硬化性心脏病(冠心病)诊断中的价值。方法回顾性分析126例疑似冠心病的患者64-SCTCA和CAG检查资料,并对两组资料进行对比分析。结果 64-SCTCA和CAG检查结果中可用于评价的病变血管段支数比较,差异无统计学意义(P>0.05)。CAG共发现≥50%狭窄节段242个,64-SCTCA共发现≥50%狭窄节段199个,两种检查方法对病变狭窄的显示情况比较,差异无统计学意义(P>0.05)。全部126例冠心病患者中有91%通过64-SCTCA发现(110/121)。64-SCTCA诊断冠状动脉病变血管的敏感性、特异性、阳性预测值、阴性预测值分别为81.6%、98.8%、79.5%、99%。结论 64-SCTCA可作为冠心病无创、便捷、可靠的检查方法。

Objectives To investigate the clinical value of 64-slice computed tomography coronary angiography（64-SCTCA） for the diagnosis of coronary artery disease,comparing with coronary angiography（CAG）.Methods We retrospectively analyzed the data of 126 patients who were suspected to have coronary artery disease undergoing 64-SCTCA and CAG,and compared the data of the two methods.Results The could-be-estimated number of lesions between 64-SCTCA and CAG had no significant difference（P0.05）.A total of 199 relevant lesions（stenosis diameter≥50%） were detected by 64-SCTCA and 242 relevant lesions（stenosis diameter≥50%） were detected by CAG.The discovery ability of stenosis lesions between the two methods had no significant difference（P0.05）.Ninety-one percent of patients with coronary artery disease were detected by 64-SCTCA in 126 patients.The sensitivity,specificity,positive and negative predictive values for 64-SCTCA were 81.6%,98.8%,79.5%,99%.Conclusions 64-SCTCA is a noninvasive,easy to perform,accurate way to diagnose coronary artery disease.