期刊文献+

超敏C反应蛋白和血清尿酸水平与冠状动脉病变程度的关系的探讨 被引量:1

下载PDF
导出
摘要 目的探讨超敏C反应蛋白(hs-CRP)、血清尿酸(UA)与冠状动脉病变程度的关系。方法检测正常对照组和冠状动脉造影确诊的冠心病患者超敏C反应蛋白(hs-CRP)、血清尿酸(UA)、低密度脂蛋白胆固醇(LDL-C),分析检测指标与冠状动脉病变程度的关系。结果冠心病患者hs-CRP、UA和LDL-C水平均高于正常对照组及冠状动脉造影阴性组(P<0.01),后者血清3项指标水平虽然较正常对照组有所升高,但仅超敏C反应蛋白有差异(P<0.01)。hs-CRP、血清UA和LDL-C水平与病变程度相关。结论联合检测hs-CRP、UA和LDL-C有助于对冠状动脉病变的诊断和严重程度的评估。
作者 郑丽丽
出处 《心脑血管病防治》 2010年第6期451-452,共2页 CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT
  • 相关文献

参考文献4

  • 1卓绮玲,林增文.高敏-CRP——心血管疾病的独立危险因子[J].国外医学(临床生物化学与检验学分册),2004,25(1):72-73. 被引量:40
  • 2Culleton BF,larson MG,Kannel WB,et al.Serum uric acid and risk forcardiovascular disease and death;the framingham heart study[J].Ann Intern Med,1999,131(1):7-13.
  • 3De Ferranti SD,Rifai N.C-reactive protein and cardiovascular disease:areview of risk predicition and intervention[J].Clin chim Acta,2002,317:1-15.
  • 4党爱民,刘国仗.尿酸与心血管事件[J].中华心血管病杂志,2003,31(6):478-480. 被引量:244

二级参考文献45

  • 1Gertler MM, Garn SM, Levine SA. Serum Uric acid in relation to age and physique in health and in coronary heart disease. Ann Intern Med, 1951,34 : 1421-1431.
  • 2Beard Jt. Serum uric acid and coronary heart disease. Am Heart J,1983,106:397-400.
  • 3Alderman MH, Cohen H, Madhavan S, et al. Serum uric acid and cardiovascular events in successfully treated hypertensive patients.Hypertension, 1999,34 : 144-150.
  • 4Bickel C, Rupprecht HI, Blankenberg S, et al. Serum uric acid as an independent predictor of mortality in patients with angiographical]y proven coronary artery disease. Am J Cardiol, 2002,89:12-17.
  • 5Brand FN, McGee DL, Kannel WB, et al. Hyperuricemia as a risk factor of coronary heart disease: The Framingham Study. Am J Epidemiol, 1985,121 : 11 -18.
  • 6Bonora E, Targher G, Zenete MB, et al. Relationship of uric acid concentration to cardiovascular risk factors in young men. Role of obesity and central fat distribution. The Verona Young Men Atheroaclerosis Risk Factors Study. Int J Obes Relat Metab Disord,1996,20:975-980.
  • 7Rathmann W, Funkhouser E, Dyer R, et al. Relations of hyperuricemia with the various components of the insulin resistance syndrome in young black and white adults: the CARDIA study.Coronary Artery Risk Development in Young Adults. Ann Epidemiol, 1998,8:250-261.
  • 8Ward HI. Uric acid as an independent risk factor in the treatment of hypertension.Lancet, 1998,352:670-671.
  • 9DeScheeder IK, van de Kraay AM, Lamers JM, et al. Myocardial malodialdehyde and uric acid release after short-lasting coronaryy occlusions during angioplasty: potential mechanisms for free radical generation. Am J Cardiol, 1991,68:392-395.
  • 10Ginsberg MH, Kozin F, O'Malley M. et al. Release of platelet constituents by monosodium urate crystals. J Clin Invest, 1997,60:999-1007.

共引文献281

同被引文献7

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部