5-甲基-4-乙氧羰基-3-腈基呋喃胺二甲亚砜Schiff碱的合成及表征

Synthesis and Characterization of 5-Methyl-4-ethoxycarbonyl-3-cyano Furan Amine Dimethyl Sulfoxide Schiff Base

以氯代乙酰乙酸乙酯与丙二腈为主要原料、乙醇为溶剂、三乙胺为催化剂,合成了中间体5-甲基-4-乙氧羰基-3-腈基呋喃胺(Ⅰ),中间体Ⅰ再与二甲亚砜反应合成5-甲基-4-乙氧羰基-3-腈基呋喃胺二甲亚砜Schiff碱(Ⅱ)。目标化合物Ⅱ通过IR、1HNMR、MS进行了表征。

With chloro ethyl acetoacetate and propanedinitrile as main raw materials,alcohol as solvent,and triethylamine as catalyst,an intermediate 5-methyl-4-ethoxycarbonyl-3-cyano furan amine（Ⅰ） was synthesized.And then 5-methyl-4-ethoxycarbonyl-3-cyano furan amine dimethyl sulfoxide Schiff base（Ⅱ） was obtained by reaction of the intermediate Ⅰwith dimethyl sulfoxide.The object compound was characterized by IR,^1HNMR and MS.