1Brooks AS, Oostra BA, Hofstra BMW. Studying the genetics of Hirschsprung' s disease : unraveling an oligogenic disorder. Clin Genet ,2004,67 : 6-14.
2Gariepy CE. Developmental disorders of the enteric nervous system: genetic and molecular bases. J Pediatr Gastroenterol Nutr,2004,39:5- 11.
3Agati V, Schuchardt AD, Larsson-blomberg L, et al. Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor RET. Nature, 1994,367:380-383.
4Takahadhi M. The GDNF/RET signaling pathway and human diseases. Cytokine Growth Factor,2001, 12:361-373.
5Gianino S, Grider JR, Gresswell J, et al. GDNF availability determines enteric neuron number by controlling precursor proliferation. Development, 2003,130:2187-2198.
7Lvanchuk SM, Myers SM, Eng C, et al. De nono mutation of GDNF, ligand for the RET/GDNF-alpha receptor complex, in Hirschsprung disease. Hum Mol Genet, 1996,5:2023-2026.
8MeCallion AS,Chakravarti A. EDNRB/EDN3 and Hirschsprung disease type Ⅱ. Pigment Cell Res,2001,14 : 161-169.
9Gariepy CE. Genetic basis of Hirschsprung disease implications in clinical practice. Mol Genet Metab,2003,80:66-73.
10Carrasquillo MM, McCallion AS, Puffemberger EG, et al. Genomewide association study and mouse model identify interaction between RET and EDNRB pathways in Hirschsprung disease. Nat Genet, 2002,32 : 237- 244.
