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盐酸戊乙奎醚注射液在经尿道前列腺电切除术术前应用的效果观察

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摘要 目的观察盐酸戊乙奎醚注射液(长托宁)、阿托品用于经尿道前列腺电切除术术前用药时对患者的唾液分泌、视觉模拟(VAS)口干评分及心率的影响。方法选择60例良性前列腺增生症择期行经尿道前列腺电切除术患者随机分为长托宁组、阿托品组,各30例。术前30min长托宁组肌内注射长托宁0.01mg/kg,阿托品组肌内注射阿托品0.5mg。在麻醉方法相同的情况下,分别观察2组在用药前和用药后50min时的唾液分泌、VAS口干评分情况及心率的变化。结果 2组给药后50min时唾液分泌明显减少,与用药前比较差异有统计学意义(P<0.05),2组间比较差异无统计学意义(P>0.05)。2组VAS口干评分给药后50min时明显高于给药前(P<0.05),2组间比较差异无统计学意义(P>0.05)。长托宁组给药后50min时心率与给药前相比差异无统计学意义(P>0.05),阿托品组给药后50min时心率与给药前相比差异有统计学意义(P<0.01)。结论长托宁作为经尿道前列腺电切除术术前用药,在抑制唾液分泌的同时,并不增快心率,比阿托品更有优势。
作者 王顺
出处 《临床合理用药杂志》 2010年第23期53-54,共2页 Chinese Journal of Clinical Rational Drug Use
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