新疆和田地区151名维吾尔族孤儿病毒性肝炎感染状况调查

Hepatitis virus infection of 151 orphans in Hetian region of Xinjiang

目的了解新疆和田地区特殊群体病毒性肝炎的感染状况,为预防该人群病毒性肝炎提供科学依据。方法应用酶联免疫吸附试验(ELISA)检测新疆和田地区2所福利学校151名6～19岁孤儿血清的病毒性肝炎特异性指标,并进行统计学分析。结果该人群甲型病毒性肝炎自然感染率为92.72%,其中男性感染率为92.63%,女性感染率为92.86%;乙型病毒性肝炎表面抗原(HBsAg)阳性率为0.66%,乙型肝炎病毒(HBV)总感染率为11.92%,其中男性感染率为17.89%,女性感染率为1.79%;戊型病毒性肝炎感染率为8.61%,其中男性感染率为8.42%,女性感染率为8.93%;随着年龄的增长各型病毒性肝炎的感染率都呈上升趋势。结论该群体甲型病毒性肝炎和戊型病毒性肝炎感染率均高于新疆同年龄段的平均水平,乙型病毒性肝炎HBsAg阳性率、HBV总感染率明显低于新疆同年龄段的平均水平。加强对这一群体的卫生宣传,改善卫生条件,积极预防甲肝及戊肝等肠道传播疾病,并进行乙型病毒性肝炎疫苗的接种是十分必要的。

Objective To learn the infected situation of hepatitis virus in special group and to provide scientific proof to prevent the infection of hepatitis virus.Methods Hepatitis virus indexes were measured in 151 orohans from two welfare school in HeTian of XinJiang using enzyme linked immunosorbent assay（ELISA） and statistical analysis.Results The spontaneous infection rate of hepatitis A virus was 92.72%,in which,male accounted for 92.63%,female accounted for 92.86%.The positive rate of HBsAg in hepatitis B virus was 0.66%.The total infection rate of hepatitis B virus was 11.92%,in which,male accounted for 17.89%,female accounted for 1.79%.The infection rate of hepatitis E virus was 8.61%,in which male accounted for 8.42%,female acconted for 1.79%.With the growth of age,the infection rates of hepatitis virus taken on an ascending trend.Conclusion The infection rates of hepatitis A virus and hepatitis E virus in this group were all higher than the average level in XinJiang.The positive rate of HBsAg and the total infection rate of HBV were significantly lower than the average in XinJiang.So it is necessary to strengthen the health propaganda,to improve health condition and vaccine bacterin of HBV actively.Key wors： Hepatitis;viral;human;prevalence;orphans;He Tian;uighur nationality