留置导尿致尿路感染病原菌分布及耐药性分析

Pathogenic Bacteria Distribution and Drug Resistance in the Urinary Tract Infection Caused by Urethral Catheterization

目的:为留置导尿致尿路感染临床合理选用抗菌药物提供依据。方法:对沈阳医学院两所附属医院2008年12月至2009年10月术后留置导尿患者尿液进行细菌培养、鉴定及药物敏感试验。结果:912例患者共分离出226株病原菌,革兰阴性菌129株(57.08%),革兰阳性菌90株(39.82%),真菌7株(3.09%)。结论:留置导尿所致尿路感染仍以革兰阴性菌感染率较高,不同病原菌敏感药物存在较大差异,建议用药前进行药物敏感试验。

Objective： To provide the basis for using antimicrobial drugs legitimately in the urinary tract infection caused by catheterization in clinic.Method：Bacterial culture,identification and drug sensitivity test was utilized with the urine of patients after catheterization in the two affiliated hospitals of Shenyang Medical College from December 2008 to October 2009.Result：226 pathogens were isolated from 912 cases.In which,129 pathogens were G-bacteria（57.08%）,90 pathogens were G＋ bacteria（39.82%）,7 pathogens were fungus（3.09%）.Conclusion：Gram-negative bacteria infection rate is still higher in the urinary tract infection due to indwelling catheter.Sensitive drugs are quite different to different pathogens.To suggest drug resistance should be tested before treatment.