213例青年缺血性脑卒中病因及危险因素分析

Analysis for the cause of disease and the risk factors for ishemic stroke in 213 young adults

目的探讨青年缺血性脑卒中的病因及危险因素,以期早期对因治疗,最大限度地降低致死率和致残率。方法对213例青年缺血性脑卒中病例按年龄分两组,进行回顾性分析。结果青年Ⅰ组在大动脉硬化和小动脉闭塞病因方面低于青年Ⅱ组,两组比较有显著性差异(P<0.05)。在其它原因、心源性栓塞方面青年Ⅰ组高于青年Ⅱ组,两组比较有显著性差异(P<0.05)。高血压病、高脂血症、糖尿病等是青年Ⅱ组的主要危险因素,而血管炎、夹层动脉瘤、高同型半胱氨酸血症等是青年Ⅰ组的主要危险因素。结论青年缺血性脑卒中不同年龄段其病因及危险因素仍有不同的特点,特别是35岁以下的病例应尽可能寻找其临床少见的病因及危险因素。

Objective To investigate the cause of disease and the risk factors for ischemic stroke in Youth （17~34 y）,in order to maximally reduce the mortality and disability with pathogenic treatment in early period.Methods 213 young cases with ischemic stroke are divided into two groups by age（group Ⅰ：35 y,and group Ⅱ：35~45 y）,then a retrospective analysis is used throughout this study.Results For cause of disease,compared the incidence of large artery atherosclerosis of and small arterial occlusive,group Ⅰ is significantly lower than that of group Ⅱ（P0.05）.Compared the incidence of Cardiac embolism,group Ⅰ is significantly higher than that of group Ⅱ（P0.05）.Hypertension,hyperlipidemia,diabetes mellitus are the main risk factors for group Ⅱ,and vasculitis,hyperhomocysteinemia,dissection aneurysms of the aortic arch are the main risk factors for group Ⅰ.Conclusions For the cause of disease and the risk factors for ischemic stroke in youth,there are different characteristics for the different age groups,especially for the patients under 35 y,it＇s more important and necessary to find out the rare disease causes and risk factors.