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尿胰蛋白酶原-2诊断急性胰腺炎的价值 被引量:3

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摘要 目的:判断胰尿蛋白酶原-2(尿TPG-2)诊断急性胰腺炎的价值。方法:比较急性胰腺炎起病4 h内、4~120 h之间以及120 h后尿TPG-2和血清淀粉酶的阳性率,了解尿TPG-2诊断急性胰腺炎的敏感性。比较在其他急腹症时,尿TPG-2和血清淀粉酶的阳性率,了解尿TPG-2诊断急性胰腺炎的特异性。结果:起病4 h内患者75例,蛋白酶原-2阳性51例(68%),血清淀粉酶阳性39例(52%),尿TPG-2阳性率高于血清淀粉酶阳性率(P<0.05)。起病4-120 h之间,患者211例,尿TPG-2阳性204例(96.7%),血清淀粉酶阳性199例(94.3%),尿TPG-2阳性率和血清淀粉酶阳性率之间无差异(P>0.05)。起病120 h之后,患者211例,蛋白酶原-2阳性97例(46.0%),血清淀粉酶阳性62例(29.4%),尿TPG-2阳性率高于血清淀粉酶阳性率(P<0.05)。肠梗阻、胆系结石以及十二指肠球部溃疡所构成的急腹症45例,尿TPG-2阳性11例(24.4%),血清淀粉酶阳性4例(8.9%),尿TPG-2阳性率和血清淀粉酶阳性率之间无显著差异(P>0.05)。结论:尿TPG-2是诊断急性胰腺炎的可靠指标,早期与回顾性诊断急性胰腺炎,较血清淀粉酶敏感。
出处 《南京医科大学学报(自然科学版)》 CAS CSCD 北大核心 2010年第12期1802-1803,共2页 Journal of Nanjing Medical University(Natural Sciences)
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