角石蕊中松萝酸的提取及生物活性研究

Extraction and Bioactivity of Usnic Acid from Cladonia cornuta (L.) Hoffm.

以采自新疆天山后峡地区角石蕊为实验材料,从角石蕊中提取松萝酸,并对其抗氧化活性和抑菌活性进行测定,以松萝酸标准品和VC为参照物。结果表明:样品具有较强的还原力和清除羟自由基、超氧阴离子自由基的能力;松萝酸对细菌的生长均有明显的抑制作用,其中对变形杆菌的抑制作用最强,对大肠杆菌的抑制作用次之,对金黄色葡萄球菌的抑制作用较弱,对枯草芽孢杆菌的抑制作用最弱。

Cladonia cornuta （L.） Hoffm harvested from Xinjiang’s Tianshan No.1 glacier was used as the experimental material to extract usnic acid and determine its antioxidant activity and antibacterial activity. Results indicated that the usnic acid extracted from Cladonia cornuta （L.） had higher reducing power and antioxidant capacity. Meanwhile, usnic acid exhibited a significant inhibition on the growth of bacteria such as Proteusbacillus vulgaris, Escherichia coli, Staphylococcus aureus and Bacillus subtilis.