摘要
根据我国免疫调节功能食品的评价方法,对添加乳蛋白水解物的免疫增强乳制品的免疫调节作用进行评价。在实验中,采用Balb/c小鼠建立免疫低下模型,以不同剂量的配方奶粉对小鼠进行灌胃实验,分别进行免疫脏器质量、细胞免疫功能、体液免疫功能、单核-巨嗜细胞功能等指标检测。结果表明:在所选定的剂量范围内,添加乳源蛋白水解物的老年奶粉和婴幼儿(三段)奶粉结果均为阳性,因此可判定配方奶粉具有免疫增强作用。
To understand the immunoregulatory function of formula milk powder added with lactoprotein hydrolysates, different doses of infant formula milk powder and middle-aged and senior formula milk powder with and without the additions of casein and milk whey protein hydrolysates were orally administered to the Balb/c mouse model with immunosuppression induced by intraperitoneal injection of cyclophosphate （Cy） for 15 successive days, respectively. Spleen index, thymus index, cellular immune response, humoral immune function and phagocytic function of mononuclear macrophage were determined on the second day after the last administration. It was found that the evaluation results of infant formula milk powder and middle-aged and senior formula milk powder added with lactoprotein hydrolysates were both positive, thus proving that adding lactoprotein hydrolysates enhances the immunoregulatory function of formula milk powder.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2010年第23期360-365,共6页
Food Science
基金
天津市科技支撑计划重点项目(07ZCKFNC00200)
关键词
乳蛋白水解物
配方奶粉
免疫调节功能
lactoprotein hydrolysates
formula milk powder
immunoregulatory function
