摘要
随着新一代测序技术的发展,高通量测序技术的应用越来越广泛,其产生的海量数据的存储、查询需要专门的数据库辅助,NCBI的SRA(Sequence Read Archive)数据库是高通量测序存储的代表,本文对SRA数据库的组织架构,数据形态作了综述分析,并对其存贮的数据进行了总结。
Next-generation DNA sequencing technology has become widely available and been applied to biological and biomedical research.Tremendous amount of data had been dramatically generated and accumulated.It becomes indispensable to store,query and manage these kinds of data using specially designed databases,among which SRA(Sequence Read Archive) established by NCBI was widely used and accepted.Here,we described data-organization of this database and summarized currently available data in SRA and their applications.
出处
《生命的化学》
CAS
CSCD
北大核心
2010年第6期959-963,共5页
Chemistry of Life
基金
上海工程技术大学科技发展基金项目(A-2500-10-01005)资助
关键词
高通量测序
SRA数据库
next-generation DNA sequencing
SRA database