摘要
目的:通过脉搏指示剂连续心排量(PICCO)监护仪和血气分析,观察6%羟乙基淀粉(万汶)和5%白蛋白扩容治疗后对重度子痫前期并发毛细血管渗漏综合征(CLS)患者肺功能的影响。方法:选取62例重度子痫前期并发CLS产后患者,随机分为万汶组(30例)和白蛋白组(32例),采用PICCO监护仪,在扩容前、在扩容后8、16、24h记录血管外肺水指数(EVLWI)、取动脉血测定血气、计算氧合指数和肺泡动脉氧分压差(P(A-a)O2)及呼吸指数(RI)。结果:万汶组扩容后8、16、24h不同时间点EVLWI、P(A-a)O2和呼吸指数显著低于治疗前(P<0.05),万汶组扩容后氧合指数明显高于扩容前(P<0.05)。白蛋白组扩容后8、16、24hEVLWI、P(A-a)O2和呼吸指数显著高于万汶组(P<0.05);白蛋白组氧合指数明显低于万汶组(P<0.05)。结论:万汶扩容治疗不影响重度子痫前期并发CLS的肺功能,与其治疗毛细血管渗漏综合征有关。
Objective:To observe the effect of 6%hydroxyethyl starch(Voluven)or 5%albumin on lung function in severe preeclampsia combined with capillary leak syndrome.Method:Sixty two postpartum patients undergoing volume expansion were divided randomly into two groups:group voluven(30cases)and group albumin(32cases).Extra-vascular lung water index(EVLWI)and the blood gas was carried on at the same time,respiratory index(RI)and P(A-a)O2were calculated in the two groups at 8,16and 24hours after volume expansion.Result:Compared with group voluven,the extra vascular lung water index(EVLWI),P(A-a)O2and repiratory index(RI)of group albumin was obviously increased(P〈0.05).The oxygenation index of group albumin was significately lower than that of group voluven(P〈0.05).Conclusion:Voluven can improve lung function after volume expansion,which is related to capillary leak syndrome(CLS).
出处
《临床急诊杂志》
CAS
2010年第5期281-283,共3页
Journal of Clinical Emergency
关键词
羟乙基淀粉
白蛋白
肺功能
重度子痫前期
毛细血管渗漏综合征
hydroxyethyl starch
albumin
lung function
preeclampsia
severe preeclampsia
capillary leak syndrome