苏北农村中老年高血压人群代谢综合征流行病学调查

Epidemiological Investigation On The Metabaolic Syndrome In the Middle Aged And Aged Hypertension Population In Rural Areas Of Subei

目的了解苏北农村地区中老年高血压人群中代谢综合征(MS)的患病情况。方法对赣榆、东海县农村45～75岁原发性高血压人群进行流行病学调查,测量身高、体重、腰围、血压、血脂、空腹血糖,分别按照国际糖尿病联盟(IDF)和中华医学会糖尿病分会(CDS)的MS诊断标准计算患病率,并对性别、年龄、高血压水平(Ⅰ、Ⅱ、Ⅲ级)等影响因素进行相关分析。结果共调查11089人(男3985人,女7104人),IDF标准MS总患病率为44.3%,其中男、女MS患病率分别为25.4%、54.9%;CDS标准MS总患病率为37.0%,2种诊断标准的符合率为79.9%;女性BMI均值达26.1±4.9 Kg/m2,腰围超标者显著多于男性;已接受降压药物治疗的人群MS患病率高于新发高血压人群。结论苏北农村地区中老年高血压人群的MS患病率高于我国一般中老年人群的平均水平;45～75岁区间,男性MS患病率随年龄增加而显著降低,女性变化不大。肥胖女性高血压患者是MS的极高危人群。

Objective To estimate epidemiological characteristics of the metabaolic syndrome （ MS ） in middle aged and aged hypertension population in rural areas of Subei. Methods An epidemiological investigation was conducted in the rural communities of two counties （ Ganyu and Donghai ） in lian yungang city among primary hypertension population aged 45 - 75 years. Height, weight, waistline, blood pressure （BP） , blood lipid, fasting plasma glucose（ FPG ） of all subjects were measured . Then according to the diagnosic standards of MS proposed by International Diabetes Federation （IDF） and Chinese Diabetes Society （CDS） , we calculated the prevalence rate. And relative analysis of factors affected MS were studied, such as sex, age and the level of BP （ Ⅰ、Ⅱ、Ⅲ）. Results A total of 11 089 subjects （3 985 males and 7 104 females） were investigated, according to IDF standard, total prevalence rate of MS was 44.3%, and the rate was 25.4% in males and 54.9% in females. By CDS standard, the total rate was 37.0%. The accordance rate of these two standards was 79. 9%. The average value of BMI in females reached 26.1±4.9 Kg/m2, females that whose waistline exceed the standards were significantly more than males. The prevalence rate of MS in patients who has used antihypotensive drugs was higher than in newly - diagnosed hypertension patients. Conclusion First, the prevalence rate of MS in the middle aged and aged hypertension population in rural areas of Subei was higher than the national average level in middle - aged or aged people. Second, for people aged 45 to 75, the prevalence rate of MS in males decreased with increasing age, but the variation in the rate by age was much smaller for females. Third, the obese female hypertensive patients have a highly risk of MS, should be the longer the hypertension history are, the higher the prevalence rates of MS are.