烷氧基桥联双三联吡啶的简洁合成

Efficient Synthesis of Alkoxyl Bridging Bisterpyridines

通过2,2'-烷氧基双苯甲醛或4,4'-烷氧基双苯甲醛和2-乙酰基吡啶在氢氧化钠和氨水溶液中的一锅煮串联反应,方便地合成了一系列重要的烷氧基桥联的双三联吡啶配体.产物结构通过1HNMR,13CNMR和HPLC/MS表征,并测定了一个代表性化合物的单晶分子结构.

A series of novel alkoxy-bridging bis（2,2＇：6,2＇＇-terpyridine） ligands were conveniently obtained from one-pot tandem reaction of 2,2＇-alkoxy-bridging or 4,4＇-alkoxy-bridging dialdehydes with excess of 2-acetylpyridine in sodium hydroxide solution and aqueous ammonia solution, respectively. The structures of the synthetic bisterpyridines were characterized by 1H NMR, 13C NMR and HPMS techniques and further confirmed by determination of single crystal structure of one representative compound.