醋酸铑催化有机反应研究进展

The Development of Organic Reaction Catalysed by Rhodium Acetate

叙述了醋酸铑催化分解α-重氮羰基化合物生成的金属卡宾参与的有机反应,反应类型大体可以分为环化反应、插入反应和生成叶立德反应3类。铑(II)卡宾以及铑(II)金属卡宾与反应体系中杂原子作用生成的叶立德活性中间体,随后可以进行多种有机转化,作为一步合成多化学键、多官能团有机化合物的新方法,在天然产物和大分子化合物的合成中已得到了广泛的应用。

Transition-metal catalysts have been widely utilized in many organic syntheses. Rhodium acetate was found to be an efficientcatalyst for organic reactions. The purpose of this review is to give an overview of the various reactions of the Rh2 (OAc)4-stabilized carbenoids derived from α-dizao-oxo-compounds. The types of these reactions include cyclication reaction, insertion reaction and the formation of ylides. The results show that the Rh(Ⅱ) carbenoids and the reactive ylide intermediates produced from the Rh(Ⅱ)carbenoids with the heteroatom of the system can undergo many organic translations and give enormous new synthetic methods to prepare compounds containing many function groups in one step.