室间隔缺损介入治疗与手术治疗效果的对比研究

The therapeutic efficacy of interventional therapy and operation for ventricular septal defect

目的探讨室间隔缺损(VSD)介入封堵治疗(国产封堵器)的治疗效果,并与外科手术方法进行比较。方法收集符合单一左向右分流VSD 60例,应用国产封堵器介入治疗,研究其可行性及早中期疗效,并与外科手术组比较在疗效、费用、并发症、输血量、住院时间等方面的差异。结果两组手术成功率均为100%,介入封堵组均未输血,外科手术组均行输血治疗(P<0.01);术后住院时间介入封堵组少于外科手术组(P<0.01);并发症介入封堵组少于外科手术组(P<0.01);治疗费用两组比较差异无统计学意义(P>0.05)。结论应用国产封堵器介入封堵治疗单一VSD操作简单、安全,损伤小,成功率高,早中期疗效满意,与外科手术比较不需输血,住院时间短,并发症少,治疗费用相当。

Objective To investigate the therapeutic efficacy of interventional therapy and operation of ventricular septal defect（VSD）.Methods Sixty patients with left-to-right shunt ventricular septal defect were collected,interventional therapy was used for blockage,and early metaphase therapeutic effect and feasibility were studied.Meanwhile,the therapeutic effect,cost,complication and volume of blood loss,time to in-hospital were compared with surgery group.ResultsThe achievement ratio of two therapy ways were 100%（P0.05）;and the volume of blood loss,time to in-hospital of the group of interventional therapy are significant increased compared with the control group of surgery（P0.05）.Conclusion Interventional therapy is an efficacious way to therapy ventricular septal defect.