不同药物在股癣治疗中的效果比较

The Effects Comparison of Different Drugs in the Patients with Tinea Cruris

目的比较不同药物在股癣治疗中的效果,以为股癣的治疗提供依据。方法选取2008年3月至2010年4月于彭州市人民医院进行治疗的100例股癣患者为研究对象,将其随机分为A组(硝酸舍他康唑软膏组)50例和B组(咪康唑软膏组)50例,后将两组患者的治疗有效率、不良反应发生率及治疗前、后的皮损中央及边缘部位的T淋巴细胞亚群进行检测及比较。结果经研究比较发现,A组的治疗总有效率高于B组,P<0.05,而两组患者不良反应发生率无显著性差异,P>0.05,治疗1、2、4周时皮损中央及边缘部位CD3、CD4及CD8均低于B组,P均<0.05,均有显著性差异。结论在股癣的治疗中采用硝酸舍他康唑霜进行治疗,综合疗效较佳,值得临床推广应用。

Objective To compare the effects of different drugs in the patients with tinea cruris,in order to provide evidence for the treatment of tinea cruris.Methods 100 patients with tinea cruris who were treated in Pengzhou people＇s hospital from March 2008 to April 2010 were selected as research object,and they were randomly divided into group A（Sertaconazole Nitrate Ointment.Group）50 cases and group B（Miconazole Nitrate Ointment group）50 cases.Then the effective rate of treatment,incidence of adverse reactions and T Lymphocyte Subsets of skin lesions central and edge of the two groups before and after the treatment at the first,second,forth and sixth week were detected and compared.Results The effective rate of treatment of the group A was higher than that of group B,P0.05,but the incidence of adverse reactions of the two groups had no significant difference,P0.05,the CD3,CD4 and CD8 of skin lesions central and edge of the group A at the first,second and forth week were all lower than those of group B,P0.05,there were significant differences.Conclusion The effects of Sertaconazole Nitrate Ointment in the patients with tinea cruris is better,and comprehensive therapeutic effect has obvious superiority,and it is worthy of popularization and application.