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扭曲肉芝软珊瑚的化学成分(英文) 被引量：1

Chemical Constituents of Sarcophyton tortuosum
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摘要 目的:研究扭曲肉芝软珊瑚的化学成分。方法:综合利用各种层析方法分离和纯化化合物, 并利用光谱学和理化性质来鉴定化合物结构。结果:从中分离得到5个化合物, 分别鉴定为 brassicolide (1), emblide (2),methyl tortuoate A (3), methyl tortuoate B (4), (24S)-24-methylcholestane-1,3, 5, 6, 25-pentol 25-monoacetate (5)。结论:化合物1,2和5都是首次从该珊瑚中分离得到。 AIM： To study the chemical constituents of Sarcophyton tortuosum. METHODS： The chemical constituents were isolated and purified by various chromatographic techniques. Their structures were determined on the basis of physical properties and spectroscopic data. RESULTS： Five compounds were isolated and elucidated as brassicolide （1）, emblide （2）, methyl tortuoate A （3）, methyl tortuoate B （4）, and （24S）-24-methylcholestane-1, 3, 5, 6, 25-pentol 25-monoacetate （5）. CONCLUSION： Compounds 1, 2 and 5 were isolated from this species for the first time.
作者 贾睿 施艳红 何培民 郭跃伟
机构地区 上海海洋大学水产与生命学院 中国科学院上海药物研究所
出处 《中国天然药物》 SCIE CAS CSCD 北大核心 2010年第6期422-424,共3页
基金 supported by the National Science & Technology Major Project (No 2009ZX09301-001) Natural Science Foundation of China (Nos 21072204, 30730108 and 20721003) Science Foundation for the Excellent Youth Scholars of Shanghai (No ssc09001) STCSM International Cooperation Project between SIMM/China and ICB/Italy (No 10540702900) NSFC-TRF International Cooperation Project (No 20911140471) the CAS Key Project (grant KSCX2-YW-R-18)~~
关键词 扭曲肉芝软珊瑚 化学成分 二聚西松烷四萜 Sarcophyton tortuosum Chemical constituents Biscembranoids
分类号 R284.1 [医药卫生—中药学]
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参考文献10

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同被引文献18

  • 1张广文,张坤,栗原博,曾陇梅,苏镜娱.优美叶枝豆荚软珊瑚中的多羟基甾醇和神经酰胺[J].中山大学学报（自然科学版）,2007,46(3):68-71. 被引量：2
  • 2LIANG Linfu, LAN Lefu, GUO Yuewei, et al. Sartrolides A-G and bissartrolide, new cembranolides from the South China Sea soft coral Sarcophyton trocheliophorum Marenzeller [ J ]. Tetrahedron,2013,69(35) : 7381-7386.
  • 3JIA Rui, Zhang Wen, Guo Yuewei, et al. Biscembranoids formed from an α, β-unsaturated y-lactone ring as a dienophile: structure revision and establishment of their absolute configurations using theoretical calculations of electronic circular diehroism spectra [ J ]. J Org Chem, 2013,78(7) : 3113-3119.
  • 4ZHANG Cuixian, SU Jingyu, ZENG Longmei, et al. New precursor of tetraterpenoids from the soft coral Sarcophyton glaucum[J]. Nat Prod Rep,2013,27(9):782-786.
  • 5ZENG Longmei, SU Jingyu, LAN Wenjian, et al. Two new cytotoxic tetracyclic tetraterpenoids from the soft coral Sarcophyton tortuosum [ J ]. J Nat Prod, 2004, 67 ( 11 ) : 1915-1918.
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  • 8ZHANG Wen, GUO Yuewei, GU Yueheng. Secondary metabolites from the South China Sea invertebrates: chemistry and biological activity [ J ]. Curr Med Chem, 2006, 13(7) :2041-2090.
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  • 10KOBAYASHI M, HAYASHI T, HAYASHI K, et al. Marine sterols. XI. Polyhydroxysterols of the soft coral Sarcophyton: isolation and synthesis of 5a-cholestane-1β, 3β, 5, 6β- tetrol[ J]. Chem Pharm Bull, 1983,31 (6) : 1848-1855.

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中国天然药物
2010年 第6期

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