薄叶红厚壳根的呫吨酮成分(英文)

Xanthones from the Roots of Calophyllum membranaceum

目的:研究薄叶红厚壳根的乙酸乙酯部位的化学成分。方法:运用各种色谱方法进行化学成分的分离纯化, 用理化方法和波谱数据解析其化学结构。结果:分离得到 11 个呫吨酮,结构分别为 1, 7-二羟基-3-甲氧基呫吨酮(1), 1, 5, 6-三羟基呫吨酮(2), 1, 3, 6-三羟基-5-甲氧基呫吨酮(3), 1, 3, 7-三羟基呫吨酮(4), 1-羟基-6, 7-二甲氧基呫吨酮(5), 3, 5-二羟基呫吨酮(6), 4-羟基-3-甲氧基呫吨酮(7), 1, 2-二甲氧基呫吨酮(8), 1, 3, 5-三羟基呫吨酮(9), pyranojacareubin(10), 1, 4, 5-三羟基呫吨酮(11)。结论:所有的化合物均为首次从该植物中分离得到, 其中 1, 3-7, 9 为首次从该属植物中分离得到。

AIM： To investigate chemical components of the ethyl acetate fraction of Calophyllum membranaceum. METHODS： Isolation and purification were carried out by several column chromatographic methods. Compounds were identified based on their physicochemical properties and spectral data. RESULTS： Eleven xanthones were isolated from ethanol extract of the roots of C. Membranaceum. The structures of those xanthones were elucidated as 1, 7-dihydroxy- 3-methoxyxanthone （1）, 1, 5, 6-trihydroxyxanthone （2）, 1, 3, 6-trihydroxy-5-methoxy-xanthone （3）, 1, 3, 7-trihydroxyxanthone （4）, 1-hydroxy-6, 7-dimethoxyxanthone （5）, 3, 5-dihydroxyxanthone （6）, 4-hydroxy-3-methoxy xanthone （7）, 1, 2-dimethoxyxanthone （8）, 1, 3, 5-trihydroxyxanthone （9）, pyranojacareubin （10）, and 1, 4, 5-trihydroxyxanthone （11）. CONCLUSION： All compounds are firstly isolated from this plant and compounds 1, 3-7, 9 were isolated from the Calophyllum genus for the first time.