摘要
目的观察西替利嗪联合反应停(沙利度胺)治疗慢性荨麻疹的疗效。方法收集门诊慢性荨麻疹患者(其它方法治疗不理想者)采用病例随机分组,治疗组口服反应停100 mg/日,分2次口服,盐酸西替利嗪,每日1次,每次10 mg。对照组单服盐酸西替利嗪每次10 mg,每日1次。两组疗程均为4周,疗程结束,随访1个月评价。结果治疗组有效率为72.29%,对照组有效率为33.82%。两组有效率比较差异有显著性(x^2=22.34,P=0.00)。结论西替利嗪联合反应停治疗顽固性荨麻疹是一种有效方法。
Objective To observe therapeutic efficiency of cetirizine combined with thalidomide in the treatment of chronic urticaria.Methods The cases of chronic urticaria were divided into treatment group and control group.The patients in the treatment group were orally given cetirizine and thalidomide for 4 weeks,and those in the control group were only given cetirizine for 4 weeks.Results The total effective rates in treatment group and control group were 72.29% and 33.82%respectively,there was a significant difference in the effective rates in two groups（x^2=22.34,P = 0.00）.Conclusion Compared with desloratadine for the treatment of chronic urticaria,cetirizine combined with thalidomide can increase clinical efficacy.
出处
《南华大学学报（医学版）》
2010年第6期786-788,共3页
Journal of Nanhua University(Medical Edition)
基金
湖南省自然科学基金[07JJ6162]
衡阳市科技局基础研究计划项目[2008KJ003]
关键词
荨麻疹
慢性
西替利嗪
反应停
Urticaria
Chronic
Cetirizine
Thalidomide
