参麦注射液对老年性肺炎的辅助治疗临床观察

Clinical observation of Shenmai injection on supplementary therapy of elderly patients with pneumonia

目的探讨参麦注射液辅助治疗老年性肺炎的有效性。方法将66例老年肺炎患者随机分为实验组和对照组，对照组给予常规抗感染、止咳平喘祛痰改善通气及纠正电解质紊乱等对症支持综合治疗，实验组在常规抗感染等综合措施基础上加用参麦注射液治疗。观察各组临床总疗效以及氧分压、氧合指数、二氧化碳分压及免疫球蛋白的变化情况。结果实验组总有效率为93．9％，对照组总有效率为87．9％，实验组优于对照组（P〈0．05）；治疗后实验组PaO2、PaO2，FiO2高于对照组，PaCO2低于对照组（P〈0．05）；治疗后实验组免疫球蛋白G、免疫球蛋白A、免疫球蛋白M的含量均高于对照组（P〈0．05）。结论在常规抗感染等综合治疗基础上加用参麦注射液治疗老年性肺炎，可以有效提高机体免疫功能，改善通气功能，纠正组织器官的缺氧状态，是一种有效的辅助治疗手段。

Objective To evaluate the outcome of Shenmai injection on supplementary therapy of elderly patients with pneumonia. Methods 66 patients were randomly divided into experimental group and control group, 33 cases each group. The experimental group were given conventional treatments combined with Shenmai Injection based on the con- ventional treatments, whereas the control group only underwent the same conventional treatments as the experimental group. Results The total effective rates of the experimental group and the control group were 93.9%and 87.9%, respectively, which showed a notable difference between the two groups （P〈0.05）. Arterial PaO2, oxygenation index and immunoglobulin G/A/M of the experimental group were higher than those of the control group, whereas arterial PaCO2 of the experimental group were lower than those of the control group （P 〈 0.05） Conclusions Shenmai injection may be effective in enhancing immunity, intensifying antibiotic action, improving ventilation and rectifying hypoxia in elderly patients with pneumonia.