空腹血糖及糖化血红蛋白浓度对糖尿病合并急性ST段抬高的心肌梗死患者心力衰竭的预测价值

The prognostic value of fasting glucose and hemoglobin A1c on the risk of heart failure in patients with diabetes and STEMI

目的研究糖尿病合并急性心肌梗死(AMI)患者空腹血糖(FG)、糖化血红蛋白(HbA1c)浓度对发病30 d心力衰竭(HF)的预测价值。方法 98例糖尿病合并AMI患者分为正常组及升高组,测定其FG、HbA1c浓度。并观察发病30 d时上述指标与HF的关系。结果升高组治疗前及随访30 d心功能分级、左室舒张末期内径均明显高于正常组;而左室射血分数明显低于正常组(P<0.05)。HbA1c为AMI 30 d HF预后的独立危险因子(P<0.01)。结论 HbA1c是AMI近期HF预后的独立危险因子。

Objective To investigate the prognostic value of fasting glucose（FG）and hemoglobin Alc（HbA1c）in patients with diabetes and acute myocardial infarction（AMI）on the risk of heart failure（HF）at 30-day.Methods FG and HbA1c were measured in 98 hospitalization patients with diabetes and AMI.Patients were divided into two groups by with or without HF on the time of 30-day.And estimate the relationship between FG,HbA1c and HF at 30 day.Results FG and HbA1c were observed obvious relationships on HF at 30-day in AMI（P〈0.05）.And HbA1c appears an unique independent risk factor on HF at 30-day in AMI by multivariate binary logistic regression analysis（P〈0.01）.Conclusion Hyperglycemia is a risk factor with 30-day outcome on HF in AMI.and HbAlc is an unique absolute risk factor to estimate short-term outcome in patients with diabetes and AMI.