摘要
目的监测接种甲型H1N1流感病毒裂解疫苗的不良反应。方法对134例首批接种甲型HINt流感病毒裂解疫苗者进行不良反应监测。结果28例接种者发生ADR,发生率为20.9%,共38例次,其中局部反应为7例次,全身反应为31例次。以1级反应为主,未发现其他异常反应、偶合反应和任何有临床意义的严重不良事件;不良反应主要发生于接种第1d(71.4%)或第2d(25.0oA);不良反应病程主要为1~2d,其中23倒不良反应者(82.1%)为自行缓解,5例(17.9%)曾使用药物治疗,所有不良反应发生者均治愈。结论接种甲型H1N1流感病毒裂解疫苗可能发生轻度的不良反应,一般很快自愈,该疫苗有较好的安全性。
Objective To summarize the adverse reaction of HIN1 influenza A vaccine. Methods Data of adverse reaction collected from 134 inoculated patients were analyzed. Results There were 28 cases ( 38 times) with adverse reaction, including local reaction ( 7 cases) and systemic reaction ( 31 eases). Most ADR course was in 1-2 day. In all ADR, there were 23 eases to self-healing and 5 eases treated with drugs. All ADR cases were cured. Conclusion The H1N1 Influenza A Vaccine could cause a few people with mild adverse reactions, and the symptoms were quickly self-healing.
出处
《西部医学》
2011年第1期154-155,共2页
Medical Journal of West China
关键词
甲型H1N1流感病毒裂解疫苗
不良反应
监测分析
H1N1 Influenza A Vaccine
Adverse reaction Influenza vaccine
Surveillance and Analysis