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妊娠期急性脂肪肝8例分析

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摘要 目的:探讨妊娠期急性脂肪肝的临床特点、治疗方案及预后情况,以便更早的认识,采用最合理的对孕妇胎儿影响最小的治疗方案,最大的改善围生期孕产妇及胎儿的结局。方法:对我科2006年至今收治的8例妊娠期急性脂肪肝患者的资料进行回顾性分析。结果:8例均有上消化道症状,6例伴有白细胞升高、血小板下降、低血糖;5例凝血功能障碍,1例DIC伴多脏器功能衰竭。8例患者中1例因病情严重家属放弃治疗,随访死亡,1例就诊时死胎,5例就诊时胎儿宫内窘迫,均行剖宫产,出生后转儿科。结论:妊娠期急性脂肪肝是妊娠期特发的疾病,多见于初产妇,多胎多见,男性胎儿多见。其起病急,进展快,危害大,且容易误诊,严重危及母儿安危。早期诊断、强有力支持治疗、快速终止妊娠,可明显改善预后。
机构地区 运城市中心医院
出处 《医学信息(中旬刊)》 2011年第1期95-96,共2页 Medical Information Operations Sciences Fascicule
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参考文献3

  • 1Siemens FC, Visser W, Metselaar H J, et al. The pregnancy patient with acute liver disease [ J ]. Ned Tijdschr Geneeskd, 2002, 146 (31) : 1433 - 1437.
  • 2王敬,辛虹.妊娠期急性脂肪肝研究进展[J].实用妇产科杂志,2010,26(3):192-195. 被引量:12
  • 3Browning MF, Levy HL, Wilkins Hang LE, et al. Fetal fatty oxidation defects and matemal liver diseaer in pregnancy[ J]. Obstet Gynecol,2006,107 "(1):115-120.

二级参考文献18

  • 1Jamal A Ibdah.Acute fatty liver of pregnancy:An update on pathogenesis and clinical implications[J].World Journal of Gastroenterology,2006,12(46):7397-7404. 被引量:51
  • 2Grace L. Su.Pregnancy and liver disease[J]. Current Gastroenterology Reports . 2008 (1)
  • 3Glantz A,Marschall HU,Mattsson LA.Intrahepatic cholestasis of pregnancy: Relationships between bile acid levels and fetal complication rates. Hepatology . 2004
  • 4Fesenmeier,MF,Coppage,KH,Lambers,DS,Barton,JR,Sibai,BM.Acute fatty liver of pregnancy in 3 tertiary care centers. American Journal of Obstetrics and Gynecology . 2005
  • 5Ch’ng,CL,Morgan,M,Hainsworth,I,Kingham,JG.Prospective study of liver dysfunction in pregnancy in Southwest Wales. Gut . 2002
  • 6BROWNING MF,LEVY HL,WILKINS-HAUG LE,et al.Fetal fatty acid oxidation defects and maternal liver disease inpregnancy. Obstetrics and Gynecology . 2006
  • 7Rajasri AG,Srestha R,Mitcheli J.Acute fatty liver of pregnancy-an overvi ew. Journal of Obstetrics and Gynaecology . 2007
  • 8Yang Z,Zhao Y,Bennett MJ, et al.Fetal genotypes and pregnancy outcomes in 35 families with mitochondrial trifunctionalprotein mutations. American Journal of Obstetrics and Gynecology . 2002
  • 9Mutze S,Ahillen I,Rudnik-Schoeneborn S,et al.Neither maternal nor fetal mutation (E474Q) in the alpha-subunit of the trifunctional protein is frequent in pregnancies complicated by HELLP syndrome. Journal of Perinatal Medicine . 2007
  • 10Holub M,Bodamer OA,Item C, et al.Lack of correlation between fatty acid oxidation disorders and haemolysis, elevated liver enzymes, low platelets (HELLP)syndrome?. Acta Paediatrica . 2005

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