高压氧辅助治疗重症流行性乙型脑炎的疗效研究

Effect of Adjuvant Hyperbaric Oxygen Treatment on Patients with Severe Epidemic Encephalitis B

目的观察高压氧辅助治疗重症流行性乙型脑炎临床疗效。方法就巴中市中心医院感染科对2007年7月至2009年10月期间确诊的64例重症流行性乙型脑炎患儿分为治疗组32例经高压氧辅助常规治疗,对照组32例常规治疗,将其疗效进行对比。结果治疗组病例昏迷、抽搐、发热及病理征阳性持续时间均明显短于照组(P<0.05),病死率及后遗症较对照组明显下降。结论高压氧辅助治疗重症流行性乙型脑炎的疗效优于对照组,值得推荐。

Objective To investigate the effect of adjuvant hyperbaric oxygen treatment on patients with severe epidemic encephalitis B.Methods 64 cases with severe epidemic encephalitis B in Department of Infectious Diseases,The Center Hospital of Bazhong from July 2007 to October 2009 were divided into treatment group and control group with 32 patients in each group.The treatment group received conventional therapy plus hyperbaric oxygen treatment.The control group received conventional therapy only.The clinical efficacies in the two groups were compared.Results The duration of coma,convulsion,fever and pathological positive signs of patients in the treatment group was significantly shorter than the control group（P0.05）,and mortality and complications decreased significantly compared with the control group.Conclusion Hyperbaric oxygen treatment on patients with severe epidemic encephalitis B in the treatment group has better clinical efficacy than the control group.hyperbaric oxygen treatment is recommended for patients with severe epidemic encephalitis B.