摘要
目的：观察平阳霉素（ＰＹＭ）联合地塞米松（ＤＸＭ）治疗颌面部大面积海绵状血管瘤的临床疗效和不良反应。方法：对９例临床确诊的颌面部范围６ｃｍ×７ｃｍ～１０ｃｍ×１２ｃｍ之间的大面积海绵状血管瘤，采用每周１次多点多方向瘤腔内注射药物，比较治疗前后患者的反应和肿瘤的形成变化。结果：全部病例肿瘤消失，无明显不良反应，经８个月～４６个月观察，临床治愈率为１００％。结论：ＰＹＭ联合ＤＸＭ能够治愈颌面部大面积海绵状血管瘤，具有完整保存组织正常形态和功能的特点，克服了单独使用ＰＹＭ带来的不良反应，提示两药在治疗上有协同作用。
Objective:To evaluate the effect of pingyangmycin combined with dexamethasone in the
treatment of maxillofacial massive cavernous hemangioma.Methods:The drugs were injected
through many points and directions into the cavities of the tumors in nine patients who were
diagnosed as suffering maxillofacial massive cavernous hemangioma,the sizes of which
ranged from 6 cm×7 cm to 10 cm×12 cm.The morphology of the tumor before the treatment
was compared with that after the treatment.Results:The tumors of all patients disappeared after
the treatment.No illeffect or recurrence was observed through 8～46 month follw up.The cure
rate is 100%.Conclusion:Maxillofacial massive cavernous hemangioma can be cured with the
administration of pingyangmycin combined with dexamathasone.The treatment has a good
feature of keeping the tissue in perfect state and in normal function,avoiding the adverse effect
of pingyangmycin used alone;suggesting that the two drugs exert a synergetic action in the
treatment.
出处
《山西医药杂志》
CAS
1999年第4期286-288,共3页
Shanxi Medical Journal
