慢性肺源性心脏病患者血清甲状腺激素及尿碘水平的临床观察

Clinical observations on changes for serum thyroxin and urinary iodine of chronic cor pulmonale patients

目的 探讨慢性肺心病患者甲状腺功能及尿碘水平变化。方法 应用放射免疫分析法及恒温消解尿碘分析法检测 ４１ 例不同缺氧程度的慢性肺心病患者及 ２５ 例健康对照组血清 Ｔ Ｔ３、 Ｔ Ｔ４、ｒ Ｔ３、 Ｔ Ｓ Ｈ 及尿碘水平。结果 慢性肺心病患者血清 Ｔ Ｔ３、 Ｔ Ｔ４、 Ｔ Ｓ Ｈ 及尿碘水平降低，以重度缺氧组降低幅度大，ｒ Ｔ３ 水平增高。结论 慢性肺源性心脏病患者血清 Ｔ Ｔ３、 Ｔ Ｔ４、 Ｔ Ｓ Ｈ 水平降低与缺氧程度及碘摄入量不足有关。

Objective To observe the changes of thyroid function and urinary iodine level of chronic cor pulmonale patients.Methods 25 healthy persons being taken as control,41 cases of chronic cor pulmonale patients with different anoxia were examined for their serum TT 3,rT 3,TT 4、TSH and urinary iodine levels by RIA and Acid digestion Thermostatic Assay,respectively.Results Serum TT 3,TT 4、TSH and urinary iodine level of the patients went down and serum T 3 up.Conclusions This change was correlated with insufficient iodine intake of body. [