36例IgM肾病的临床及病理分析

The clinical and pathological analysis of 36 cases of IgM nephropathy

目的 探讨成人IgM肾病的临床病理特点及预后。方法 收集本院IgM肾病 3 6例 ,对其临床表现、病理及疗效进行分析。结果 IgM肾病临床表现呈肾病综合征、血尿、血尿伴蛋白尿等多种表现 ,其组织病理和免疫病理分型也呈多样性 ,三者之间无明显相关性。所有病例予激素加免疫抑制剂治疗 ,有效率 96 7%。随访 3～ 89个月 ,未见肾功能异常改变者。结论 IgM肾病临床表现及病理分型呈多样性 ,对激素和免疫抑制剂敏感 。

Objective To investigate the clinical, pathological character and prognosis of IgM nephropathy.Methods The data of 36 cases of IgM nephropathy was reviewed and analysed.Results The clinical character of the IgMN was comprised of nephrotic syndrome, proteinuria, hematuria, proteinuria combined hematuria; and the renal pathology was varied. There was no relation between the clinical character and the pathology. The prednisone and immunosupressive was administrated, and the total effective rate was 96.7%. Patients were subjected to long-term follow-up (3～89 months), none had renal dysfunction.Conclusion The clinical character and the pathology of IgMN is varied, and sensitive to the prednisone and immunosupressive, and have the better prognosis.