云南省甲型H1N1流感重症病例流行病学分析

Epidemiological analysis of severe cases of novel influenza A(H1N1) in Yunnan,2009

目的分析云南省2009年甲型H1N1流感重症病例流行病学特征,为重症病例预防与控制提供依据。方法采用描述流行病学方法对重症病例流行病学特征进行描述分析;采用1:1配对病例-对照研究方法,对轻症病例与重症病例平均就诊时间、平均确诊时间进行比较分析。结果 2009年,云南省16个州市中有12个州市有重症病例报告,但主要集中在曲靖市和昆明市,占总重症病例的87.39%;轻症病例以学生为高发人群,重症病例以离退休人员为高发人群;轻症病例平均就诊时间、平均确诊时间均短于重症病例,差异有统计学意义(P<0.01)。结论云南省2009年甲型H1N1流感重症病例发病时间高峰为12月份,≥70岁年龄组发病为主,离退休人员为高发人群。

Objective To provide the evidence for prevention and control of severe case of novel influenza A（H1N1） through analyzing epidemiological characteristics and risk factors of severe infection in Yunnan.Methods We described epidemiological characteristics of severe cases of novel influenza A（H1N1） and conducted a 1：1 matched case-control study and compared the mean time of onset to first visit and mean time of onset to confirmation between severe cases and non-severe cases.Results Twelve prefectures reported severe cases among 16 prefectures in Yunnan.Most of severe cases（87.39%） were reported in Qujing and Kunming city.Students and peasants were at a higher risk of getting infected among non-severe cases.Whereas 70-75 age group,which were mostly retired citizens,was at a higher risk of severe infection.Non-severe cases had shorter mean time of onset to first visit and mean time of onset to confirmation;the difference between non-severe and severe cases was statistically significant（P0.05）.Conclusion The number of severe cases of novel influenza A（H1N1） peaked in December 2009.Most of severe cases were detected in Qujing and Kunming city.The eldely over 70 years and retired citizens were the populations at higher risk.