施他宁在治疗急性胰腺炎的临床应用

Clinical application of stilamin on acute pancreatitis

目的：观察生长抑素———施他宁的临床应用及在治疗急性重症胰腺炎中的作用。方法：收录本院非手术治疗的急性重症胰腺炎２８ 例，其中治疗组１８ 例，对照组１０治疗组除常规治疗外加用生长抑素———施他宁,首次250μg 冲击量3 ～5min 完成,后以3mg 连续24h ,iv ,qit,维持5 ～7d 。结果:治疗组用药后24h 胃肠减压量即明显下降,而对照组需5d ;治疗组血淀粉酶平均8d 恢复正常,而对照组需平均12d ;临床治疗时间:治疗组为(26 ±5)d ,对照组(32 ±10)d 。结论:施他宁对急性重症胰腺炎疗效明显。

OBJECTIVE:To observe the effect of Sometostatin——stilamin in treating acute fatal pancreatitis.METHODS:28 patients with acute fatal pancreatitis treated by non-operatire treatment were divided to receive conventional treatment (control group) or to receive additional stilamin,lasted for 5～7 days after i.v 250μg in 3～5 min (treatment group).RESULTS:The gasonintestinal decompression was decreased obviously in 24h (treatment group)and in 5 days(control group).The blood amylase recovered normal after 8 days(treatment group)and 12 days(control group).And the clinical cure was(26±5)d and(32±10)d respectively.CONCLUSION:Stilamin is effective in treating acute fatal pancreatitis.