北戴河区无症状高脂血症与颈动脉硬化狭窄区域分布特点及原因分析

Scattered district feature and reason analysis of hyperlipidemia without symptoms and carotid atherosclerosis stenosis in Beidaihe area

目的探讨北戴河区健康城镇居民无症状高脂血症与颈动脉粥样硬化性狭窄人群区域分布特点及特殊成因。方法将所调查的北戴河区5 408例健康成人按年龄、性别、职业、体检时间即暑期前后分成不同组,通过问卷调查、血液生化检测及颈部血管彩色多普勒超声方法综合分析。结果发现无症状高脂血症集中在>40～60岁年龄段,检出1 549例,但呈年轻化趋势,40岁以下检出高胆固醇血症313例,高甘油三酯血症333例。男性血脂异常多于女性,血脂异常与职业、暑期工作压力(P<0.05)。颈动脉硬化狭窄与高脂血症存在密切关系,232例颈动脉硬化狭窄的检出者中合并高脂血症的体检者达到140例,颈动脉硬化狭窄的检出情况在不同职业中存在性别差异情况,以公务员最明显,男女检出比率达10∶1(P<0.05)。结论北戴河区健康成人颈动脉硬化狭窄与高脂血症有关,发病与文献相比趋年轻化,暑期工作压力大的职业血脂异常人群增加。

Objective The purpose of the research was to study the scattered district feature and special reason of hyperlipidemia without symptoms and carotid atherosclerosis stenosis in heathy town adults in Beidaihe area.Methods 5 408 healthy adults were divided into different groups according to age,sex,occupation,physical examination time（before or after summer vacation time）,and questionaire analysis,blood biochemistry analysis and carotid artery color Doppler were made on the subjects.Results The population of hyerlipidemia without symptoms was 1 549 cases,the incidence of hyerlipidemia without symptoms was high from 40 to 59 years old,but the tendency was young,the population of hypercholesteremia under 40 years old was 313 cases,hypertriglyceridemia was 333 cases,dyslipemia in males was more than in females,dyslipemia relates to occupation,work pressure in summer vacation,the place where they live and so on（P〈0.05）.There are close relations between carotid atherosclerosis stenosis and hyperlipidemia,140 cases were hyperlipidemia in 232 cases who were carotid atherosclerosis stenosis,there is sex difference between different occupations in the incidence of carotid atherosclerosis stenosis,especially in public servants,male to female is 10∶1（P〈0.05）.Conclusion Carotid atherosclerosis stenosis is related to hyperlipidemia in heathy adults in Beidaihe area,and the tendency is younger and younger in contrast to literature,the population of the dyslipidemia in the professioners whose summer vacation work pressure is powerful is getting more and more.