摘要
近年来,在食品和饮用水中不断检测到农药的残留,其中一些农药,如有机氯农药已经被证明对人体具有致癌性和干扰内分泌系统的作用。我国是农药大国,现在使用的农药中有机氯农药占了很大的比例。
出处
《温州医学院学报》
CAS
2010年第6期618-621,625,共5页
Journal of Wenzhou Medical College
基金
温州市科技局科研基金资助项目(Y20070005)
参考文献27
-
1常飞,陈必良.环境激素类农药甲氧滴滴涕生殖毒性研究进展[J].国外医学(卫生学分册),2007,34(2):70-74. 被引量:7
-
2Chapin RE,Harris MW,Davis BJ,et al.The effects of perinatal/juve-nile methoxychlor exposure on adult rat nervous,immune,and reproductive system function[J].Fundam Appl Toxicol,1997,40(1):138-157.
-
3Johnson L,Staub C,Silge RL,et al.The pesticide methoxychlor given orally during the perinatal/juvenile period,reduced the spermatogenic potential of males as adults by reducing their Sertoli cell number[J].Reprod Nutri Dev,2002,42(6):573-580.
-
4Latchoumycandane C,Mathur PP.Induction of oxidative stress in the rat testis after short-term exposure to the organochlorine pesticide methoxychlor[J].Arch Toxicol,2002,76(12):692-698.
-
5Laws SC,Carey SA,Ferrell JM,et al.Estrogenic activity of octylphenol,nonylphenol,bisphenol A and methoxychlor in rats[J].Toxicol Sci,2000,54(1):154-167.
-
6Gupta RK,Miller KP,Babus JK,et al.Methoxychlor inhibits growth and induces atresia of antral follicles through an oxidative stress pathway[J].Toxicol Sci,2006,93(2):382-389.
-
7Gupta RK,Aberdeen G,Babus JK,et al.Methoxychlor and its metabolites inhibit growth and induce atresia of baboon antral follicles[J].Toxicol pathol,2007,35(5):649-656.
-
8Miller KP,Gupta RK,Greenfeld CR,et al.Methoxychlor directly affects ovarian antral follicle growth and atresia through Bcl-2-and Bax-mediated pathways[J].Toxicol Sci,2005,88(1):213-221.
-
9Eroschertko VP,Swartz WJ,Ford C.Decreased superovulation in adult mice following neonatal exposares to technical methoxychlor[J].Reprod Toxicol,1997,11(6):807-814.
-
10Golub MS,Hogrefe CE,Germann SL et al.Effects of exogenous estrogenic agents on pubertal growth and reproductive system maturation in female rhesus monkeys[J].Toxicol Sci,2003,74(1):103-113.
二级参考文献26
-
1CUMMINGS A M. Methoxychlor model for environmental estrogens [ J ] . Crit Rev Toxicol, 1997,27:367-379.
-
2NIMROD A C, BENSON W H. Xenobiotic interaction with and alteration of channel catfish estrogen receptor [ J ].Toxicol Appl Pharmacol, 1997,147 : 381-390.
-
3GAIDO K W, MANESS S C, McDONNELL D P, et al.Interaction of methoxychlor and related compounds with estrogen receptor a and β, and androgen receptor:structureactivity studies [ J ]. Mol Pharmacol, 2000, 58 ( 4 ) : 852-858.
-
4LATCHOUMYCANDANE C, MATHUR P P. Effect of methoxychlor on the antioxidant system in mitochondrial and microsome-rich fractions of rat testis[ J]. Toxicol,2002,176(1-2) :67-75.
-
5CUPP A S, SKINNER M K. Actions of the endocrine disruptor methoxychlor and its estrogenic metabolite on in vitro embryonic rat seminiferous cord formation and perinatal testis gruwth[J]. Reprod Toxicol,2001,15(3):317-326.
-
6GRAY L E, Jr, OSTBY J, MONOSSON E, et al.Environmental antiandrogens: low doses of the fungicide vinclozolin alter sexual differentiation of the male rat [ J ].Toxicol lnd Health, 1999,15(1-2) :48-64.
-
7LATCHOUMYCANDANE C, MATHUR P P. Induction of oxidative stress in the rats testis after short-term exposure to the organochlorine pesticide methoxychlor [ J]. Arch Toxicol, 2002,76(12) : 692-698.
-
8ANKLEY G T, JENSEN K M, KAHL M D, et al.Description and evaluation of short term reproductive test with the fat head minnow (Pimephales promelas)[ J ].Environ Toxicol Chem ,2001,20(6) : 1276-1290.
-
9EROSCHENKO V P, ABUEL-ATTA A A, GROBER M S,et al. Neonatal exposures to technical methoxychlor alters ovaries in adult mice [ J ]. Reprod Toxicol, 1995,9 ( 4 ) :379-387.
-
10BORGEEST C, SYMONDS D, MAYER L P, et al.Methoxychlor may cause ovarian follicular atresia and proliferation of the ovarian epithelium in the mouse [ J ].Toxicol Sci, 2002,68 (2) : 473-478.
共引文献6
-
1周建兴,马向东,马佳佳,王德堂,陈必良.甲氧滴滴涕对小鼠子宫内膜胰岛素样生长因子-1表达的调节作用[J].细胞与分子免疫学杂志,2009,25(3):255-256. 被引量:1
-
2周红宇,肖仲祥,张馨,王萍,胡国新.高效液相色谱法检测兔血浆中甲氧滴滴涕的浓度[J].温州医学院学报,2010,40(4):392-394. 被引量:2
-
3张潇云,李婉姝,张立康,阚歆,董洁,卢中秋,胡国新.兔血浆中甲氧滴滴涕及其代谢产物的高效液相色谱测定法[J].中华劳动卫生职业病杂志,2010,28(8):622-624.
-
4吕建霞,孙军,刘永强,张靖,于金玲.凝胶渗透色谱净化-气相色谱-质谱法测定肉品中的甲氧滴滴涕[J].肉类研究,2011,25(3):12-14.
-
5王春林,刘烨,曾国秀,李永春,王未恩,刘玉珍,丁定军.有机氯农药干扰妇女免疫、内分泌所致子宫内膜异位症的研究[J].现代诊断与治疗,2011,22(5):264-267. 被引量:1
-
6谢正兰,孙玉川,张媚,余琴,徐昕.岩溶地下河流域表层土壤有机氯农药分布特征及来源分析[J].环境科学,2016,37(3):900-909. 被引量:14
同被引文献25
-
1常飞,陈必良.环境激素类农药甲氧滴滴涕生殖毒性研究进展[J].国外医学(卫生学分册),2007,34(2):70-74. 被引量:7
-
2Cooney MA,Buck Louis GM.Organochlorine pesticides and endometriosis[J].Reprod Toxicol,2010,30(3):365-369.
-
3Pickford DB,Morris ID.Inhibition of gormdotropin induced oviposition and ovarian steroidogenesis in the African clawed frog by the pesticide methoxychlor[J].Aqual Toxico1,2003,62(3):179-194.
-
4Ankley GT,Jensen KM,Kahl MD,et al.Description and evaluation of short term reproductive test with the fat pead minnow(Pimephales promelas)[J].Environ Toxicol Chem,2001,20(6):1276-1290.
-
5子宫内膜异位症的诊断与治疗规范[J].中华妇产科杂志,2007,42(9):645-648. 被引量:561
-
6陈琦.子宫内膜异位症的诊治进展[J].中国社区医师(医学专业),2008,10(10):8-8. 被引量:2
-
7戴毅,冷金花,郎景和,刘珠凤,李晓燕,王艳艳.后盆腔深部浸润型子宫内膜异位症的临床病理特点及腹腔镜手术治疗效果[J].中华妇产科杂志,2010,45(2):93-98. 被引量:49
-
8邹琴,刘守亮,秦启发,骆胜超,杨素林.环境与食品中有机氯农药残留及降解的调查分析[J].公共卫生与预防医学,2010,21(1):37-39. 被引量:5
-
9王晓秋,李大金.内分泌干扰物TCDD促进子宫内膜异位症发生发展的研究进展[J].中国妇产科临床杂志,2010,11(2):158-160. 被引量:4
-
10王艳艳,冷金花,史精华,李晓燕,郎景和.子宫内膜异位症患者不同部位病灶中神经纤维分布及其与疼痛症状的关系[J].中华妇产科杂志,2010,45(4):260-263. 被引量:14
-
1常飞,陈必良.环境激素类农药甲氧滴滴涕生殖毒性研究进展[J].国外医学(卫生学分册),2007,34(2):70-74. 被引量:7
-
2杜鹃,陈必良.环境激素类农药甲氧滴滴涕与子宫内膜血管生成研究进展[J].第四军医大学学报,2009,30(10):957-958. 被引量:1
-
3海戈.环境激素:比癌症更可怕的危害[J].科学与生活,2002(7):48-50.
-
4周红宇,肖仲祥,张馨,王萍,胡国新.高效液相色谱法检测兔血浆中甲氧滴滴涕的浓度[J].温州医学院学报,2010,40(4):392-394. 被引量:2
-
5唐国华,唐朝克,贺修胜,何淑雅.甲氧滴滴涕对雄性大鼠生殖细胞毒性的影响[J].毒理学杂志,2005,19(4):275-277. 被引量:3
-
6阚歆,张潇云,王哲,董洁,王蒙蒙,胡国新.甲氧滴滴涕及其代谢产物2,2-二(4-羟基苯基)-1,1,1-三氯乙烷在大鼠体内的毒代动力学[J].中国药理学与毒理学杂志,2011,25(5):474-478. 被引量:3
-
7王宝平,马向东,马佳佳,陈必良.甲氧滴滴涕对小鼠卵巢颗粒细胞增殖和凋亡的影响[J].陕西医学杂志,2008,37(4):415-417.
-
8刘伏祥,杨静,文建国,黄河,陈庆林.甲氧滴滴涕对大鼠精子顶体酶活性的影响[J].实用预防医学,2006,13(3):493-494. 被引量:6
-
9王薇,唐伟,段宇.双酚A与甲状腺疾病研究进展[J].中华临床医师杂志(电子版),2013,7(18):163-164. 被引量:2
-
10刘伏祥.甲氧滴滴涕的毒性作用及其机制研究进展[J].解剖学杂志,2007,30(3):373-375. 被引量:3