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环境激素类农药甲氧滴滴涕研究新进展 被引量：2

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摘要 近年来,在食品和饮用水中不断检测到农药的残留,其中一些农药,如有机氯农药已经被证明对人体具有致癌性和干扰内分泌系统的作用。我国是农药大国,现在使用的农药中有机氯农药占了很大的比例。
作者 李晓珩 沈秀微 庄秀秀 胡国新 葛仁山
机构地区 温州医学院 美国人口理事会生物医学研究中心
出处 《温州医学院学报》 CAS 2010年第6期618-621,625,共5页 Journal of Wenzhou Medical College
基金 温州市科技局科研基金资助项目(Y20070005)
关键词 环境激素 甲氧滴滴涕 生殖系统 毒性 综述文献
分类号 R994.6 [医药卫生—毒理学]
  • 相关文献

参考文献27

  • 1常飞,陈必良.环境激素类农药甲氧滴滴涕生殖毒性研究进展[J].国外医学（卫生学分册）,2007,34(2):70-74. 被引量：7
  • 2Chapin RE,Harris MW,Davis BJ,et al.The effects of perinatal/juve-nile methoxychlor exposure on adult rat nervous,immune,and reproductive system function[J].Fundam Appl Toxicol,1997,40(1):138-157.
  • 3Johnson L,Staub C,Silge RL,et al.The pesticide methoxychlor given orally during the perinatal/juvenile period,reduced the spermatogenic potential of males as adults by reducing their Sertoli cell number[J].Reprod Nutri Dev,2002,42(6):573-580.
  • 4Latchoumycandane C,Mathur PP.Induction of oxidative stress in the rat testis after short-term exposure to the organochlorine pesticide methoxychlor[J].Arch Toxicol,2002,76(12):692-698.
  • 5Laws SC,Carey SA,Ferrell JM,et al.Estrogenic activity of octylphenol,nonylphenol,bisphenol A and methoxychlor in rats[J].Toxicol Sci,2000,54(1):154-167.
  • 6Gupta RK,Miller KP,Babus JK,et al.Methoxychlor inhibits growth and induces atresia of antral follicles through an oxidative stress pathway[J].Toxicol Sci,2006,93(2):382-389.
  • 7Gupta RK,Aberdeen G,Babus JK,et al.Methoxychlor and its metabolites inhibit growth and induce atresia of baboon antral follicles[J].Toxicol pathol,2007,35(5):649-656.
  • 8Miller KP,Gupta RK,Greenfeld CR,et al.Methoxychlor directly affects ovarian antral follicle growth and atresia through Bcl-2-and Bax-mediated pathways[J].Toxicol Sci,2005,88(1):213-221.
  • 9Eroschertko VP,Swartz WJ,Ford C.Decreased superovulation in adult mice following neonatal exposares to technical methoxychlor[J].Reprod Toxicol,1997,11(6):807-814.
  • 10Golub MS,Hogrefe CE,Germann SL et al.Effects of exogenous estrogenic agents on pubertal growth and reproductive system maturation in female rhesus monkeys[J].Toxicol Sci,2003,74(1):103-113.

二级参考文献26

  • 1CUMMINGS A M. Methoxychlor model for environmental estrogens [ J ] . Crit Rev Toxicol, 1997,27:367-379.
  • 2NIMROD A C, BENSON W H. Xenobiotic interaction with and alteration of channel catfish estrogen receptor [ J ].Toxicol Appl Pharmacol, 1997,147 : 381-390.
  • 3GAIDO K W, MANESS S C, McDONNELL D P, et al.Interaction of methoxychlor and related compounds with estrogen receptor a and β, and androgen receptor:structureactivity studies [ J ]. Mol Pharmacol, 2000, 58 ( 4 ) : 852-858.
  • 4LATCHOUMYCANDANE C, MATHUR P P. Effect of methoxychlor on the antioxidant system in mitochondrial and microsome-rich fractions of rat testis[ J]. Toxicol,2002,176(1-2) :67-75.
  • 5CUPP A S, SKINNER M K. Actions of the endocrine disruptor methoxychlor and its estrogenic metabolite on in vitro embryonic rat seminiferous cord formation and perinatal testis gruwth[J]. Reprod Toxicol,2001,15(3):317-326.
  • 6GRAY L E, Jr, OSTBY J, MONOSSON E, et al.Environmental antiandrogens: low doses of the fungicide vinclozolin alter sexual differentiation of the male rat [ J ].Toxicol lnd Health, 1999,15(1-2) :48-64.
  • 7LATCHOUMYCANDANE C, MATHUR P P. Induction of oxidative stress in the rats testis after short-term exposure to the organochlorine pesticide methoxychlor [ J]. Arch Toxicol, 2002,76(12) : 692-698.
  • 8ANKLEY G T, JENSEN K M, KAHL M D, et al.Description and evaluation of short term reproductive test with the fat head minnow (Pimephales promelas)[ J ].Environ Toxicol Chem ,2001,20(6) : 1276-1290.
  • 9EROSCHENKO V P, ABUEL-ATTA A A, GROBER M S,et al. Neonatal exposures to technical methoxychlor alters ovaries in adult mice [ J ]. Reprod Toxicol, 1995,9 ( 4 ) :379-387.
  • 10BORGEEST C, SYMONDS D, MAYER L P, et al.Methoxychlor may cause ovarian follicular atresia and proliferation of the ovarian epithelium in the mouse [ J ].Toxicol Sci, 2002,68 (2) : 473-478.

共引文献6

同被引文献25

引证文献2

二级引证文献3

温州医学院学报
2010年 第6期

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