高原地区反流性食管炎胃镜检查858例

Prevalence of endoscopically detected reflux esophagitis in a high-altitude area of China:an analysis of 858 cases

目的:探讨高原地区反流性食管炎(reflux esophagitis,RE)的患者情况.方法:回顾分析中国人民解放军第22医院2000-01/2009-12经胃镜检查检查的所有病例11032例,根据1999年烟台全国反流性食管病/炎研讨会制定的标准分级;对符合RE诊断病例的胃镜资料及相关信息进行分析.结果:10年间共检出RE患者858例,占总胃镜检查人数的7.78%,REⅠ、Ⅱ、Ⅲ级的检出率分别为5.65%(623/11032)、1.57%(173/11032)、0.56%(62/11032),其中轻中度者92.77%,重度者仅7.23%;高原地区RE男性组病变程度与年龄无相关性,女性组病变程度与年龄呈正相关(P<0.05).男性病例明显多于女性比例,男女比例为3.42∶1;发病年龄以30-49岁为主.食管裂孔疝见于4.43%(38/858)的病例,Barrett's食管发生率不高,仅为0.17%.结论:高原地区RE以轻中度为主,并多见于男性中青年患者.男性组病变程度与年龄无相关性,女性组病变程度与年龄呈正相关.

AIM：To analyze the characteristics of clinical epidemiology of reflux esophagitis（RE） in a highaltitude area of China.METHODS：A total of 11 032 patients undergoing endoscopy from January 2000 to December 2009 were included in this study.The data for RE patients were analyzed in terms of disease prevalence,age and gender.RESULTS：The prevalence of RE was 7.78%（858/11 032）.The prevalence of grade Ⅰ,Ⅱ and Ⅲ RE was 5.65,1.57 and 0.56%,respectively.Of all the RE patients,92.77% had mild disease and 7.23% had severe disease.Although the severity of disease showed no correlation with age in males,a positive correlation was noted in females（P〈0.05）.The ratio of male to female RE patients was 3.42：1.RE was predominantly found in patients aged 30 to 49 years.Of RE patients diagnosed with hiatal hernia（4.43%）,0.17% had Barrett＇s esophagus.CONCLUSION：The prevalence of RE is 7.78% in the high-altitude area studied.RE is milder and more common in middle-aged male patients.Although the severity of RE shows no correlation with age in males,there is a positive correlation in females.