血小板参数在甲亢患者中的变化和临床意义

Change of platelet parameters and its clinical significance in hyperthyroidism patients

目的探讨甲亢患者外周血中血小板的变化和临床意义。方法通过Sysmex XT-2000i测定甲亢患者和健康体检者的血小板总数(PLT),大血小板比率(P-LCR),血小板平均体积(MPV),血小板分布宽度(PDW)及血小板比容(PCT)等各项参数。结果甲亢患者的P-LCR、MPV、PDW及PLT与健康体检组比较差异有统计学意义(P<0.01)。结论对于甲亢患者其大血小板比率增大,可能会引起血管阻塞。因此,检测甲亢患者的血小板参数可以作为评价其诱发血栓的危险性参数。

Objective To study the platelet parameters change and its significance in hyperthyroidism patients.Methods The levels of PLT,P-LCR,MPV,PDW and PCT in hyperthyroidism patients and normal people were measured by Sysmex XT-2000I automatic haematic analyser.Results P-LCR,MPV,PDW and PLT increased significantly（P〈0.01）in hyperthyroidism patients comparedg with normal people.Conclusion The P-LCR,MPV and PDW in hyperthyroidism patients increase significantly,which may lead to blood vessel embolism.Therefore,detecting platelet parameters may be as the dangerous index to estimate the occurrence of thrombosis parameters.