摘要
随着现代分子生物学生物学技术的发展,海洋生态毒理学正进入一个新的发展阶段,一些常用的分子生物学技术应用于外来有毒物质引起的DNA损伤、基因突变、加合物形成、基因多态等的检测,大大提高了毒理学研究的整体水平。文中针对近年来新开展的几项分子生物学技术的原理及其在海洋生态毒理学领域的应用进行评述及展望。
With the development of molecular biology techniques,marine eco-toxicology is entering a new stage of development.A number of commonly molecular biology technologies were used to detect DNA damage,gene mutations,adduct formation,and gene polymorphism ion,etc.,which were caused by foreign toxic substances,and improved the overall level of toxicological studies greatly.In this review,principles of several new typical molecular biology techniques and its application in the field of marine ecological toxicology applications and development prospects were introduced.
出处
《海洋湖沼通报》
CSCD
北大核心
2010年第4期149-159,共11页
Transactions of Oceanology and Limnology
基金
海洋公益性行业科研专项经费200805031资助
山东省科技发展计划项目(2009GG10009044)资助
