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尼可地尔治疗慢性心力衰竭疗效观察 被引量:7

CLINICAL EFFECT OF NICORANDI ON CHRONIC HEART FAILURE
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摘要 目的观察尼可地尔治疗慢性心力衰竭(CHF)的临床疗效。方法将120例CHF患者随机分为治疗组和对照组。对照组采用常规治疗,治疗组在对照组治疗基础上加用尼可地尔。分别检测两组患者治疗前后左室后壁厚度(LVP)、室间隔厚度(IVS)、左室舒张末期内径(LVEDD)、左室收缩末期内径(LVESD)及左室射血分数(LVEF)。结果 与对照组治疗后比较,治疗组LVP、IVS厚度明显减小,LVEDD、LVESD明显减小,LVEF明显增加(p<0.05)。结论尼可地尔具有逆转左室重构和改善心功能的作用。 Objective To observe the clinical effect of Nicorandi on chronic heart failure(CHF).Methods 120 cases of CHF patients were randomly divided into two groups.The control group was given conventional treatment,and the treatment group was given Nicorandi on the use conventional treatment.Two groups of patients were detected left ventricular posterior wall thickness(LVP),ventricular septal thickness(IVS),left ventricular end diastolic diameter(LVEDD),left ventricular end systolic diameter(LVESD) and left ventricular ejection fraction(LVEF) before and after treatment.Results Compared with the control group,LVP,IVS thickness was significantly reduced,LVEDD,LVESD was significantly reduced,and LVEF increased significantly in treatment group.Conclusion Nicorandil can reverse left ventricular remodeling and improve cardiac function.
作者 陈爱文
出处 《现代医院》 2010年第12期13-14,共2页 Modern Hospitals
关键词 尼可地尔 慢性心力衰竭 室间隔厚度 Nicorandi Chronic heart failure Ventricular septal thickness
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