强心通脉颗粒治疗慢性心力衰竭30例的临床研究

Clinical observation on Qiangxin Tongmai granule in treating chronic cardiac failure in 30 patients

[目的]观察强心通脉颗粒治疗慢性心衰的临床疗效及安全性。[方法]观察60例慢性心衰患者,并随机分为治疗与对照组,每组30例。对照组采用西医常规治疗;治疗组采用西医常规治疗加强心通脉颗粒,用药疗程均为4周。观察患者的疗效、6 min步行距离、心功能变化及中医症候积分变化情况,并分析药物安全性。[结果]治疗组与对照组总有效率分别为86.7%、63.3%,两组有显著性差异(P<0.01);两组治疗后,比较6 min步行距离、心功能及证候积分等变化情况,治疗组优于对照组(P<0.01),具有显著统计学差异;心功能指标(P<0.05)有统计学差异,证明本药安全有效。[结论]强心通脉颗粒对于慢性心衰患者疗效确切,能够改善患者心功能,降低中医证候积分,提高慢性心衰患者生活质量。

[Objective]To observe the therapeutic effect and safety of granule of Qiangxin Tongmai in treating patients with chronic heart failure.[Methods]Sixty patients with chronic heart failure were randomly divided into two groups：the treatment group and the control group.The patients of control group were treated with routine Western medicine,while those of treatment group were treated with the granule of Qiangxin Tongmai for 4 weeks.Then the therapeutic effects were examined by testing the distance of 6 minutes walking,the function of heart,and the integrated score of TCM syndrome and the safety of the drug.[Results]The total effect ratio of treatment group was 86.7% and that of control group was 63.3%（P0.01）.Compared with the control group,the 6 minutes walking distance,the function of heart,and the TCM syndrome integrated score were significantly superior in treatment group（P0.01）.[Conclusion]The granule of Qiangxin Tongmai has a definitely therapeutic effect in treating chronic heart failure,may improve patients＇ heart function,decrease the integrated score of TCM syndrome and can improve the patients＇ quality of life as well.