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Fas/FasL在阴茎鳞癌组织中的表达分析

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摘要 目的探讨Fas/FasL在阴茎鳞癌组织中的表达及意义。方法免疫组化法分别检测40例阴茎鳞癌和20例阴茎包皮组织中及Fas、FasL蛋白的表达。结果在阴茎鳞癌和阴茎包皮组织中,Fas表达阳性率分别为40.0%和85.0%(P<0.05),FasL分别为65.0%和25.0%(P<0.05)。结论阴茎癌组织中Fas基因表达下调,FasL表达上调,使癌细胞发生免疫逃避,从而促进阴茎癌的发生。
出处 《中国中西医结合皮肤性病学杂志》 CAS 2010年第6期361-362,共2页 Chinese Journal of Dermatovenereology of Integrated Traditional and Western Medicine
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