膜引导骨组织再生术在上颌前牙区种植中的应用

Clinical retrospective study on membrane guided bone tissue regeneration technique in dental implants in the anterior maxilla

目的:探讨膜引导骨组织再生(membrane guided bone regeneration,MGBR)技术中,生物胶原膜在上颌前牙区种植骨增量中的作用。方法:选取我院2008年1月至2009年12月间上前牙区唇腭向骨量不足种植病例55例,随机分为2组,29例使用MGBR,同期植入种植体40颗(有膜组);另26例不应用MGBR,植入种植体40颗(无膜组),作为对照。观察2组患者种植前及修复前种植区牙槽骨的情况。用卡尺测量牙槽骨唇腭向厚度,用X线骨密度分析法评估平均密度的变化。采用X线片图像分析测量软件(Sidexis)和SPSS16.0软件包进行比较分析。结果:单因素分析显示,有膜组种植术前与永久修复前牙槽骨唇腭向的厚度及密度差别有统计学意义(P<0.05);种植术前与永久修复前,有膜组与无膜组牙槽骨唇腭向厚度及骨密度变化的差别有统计学意义(P<0.05)。结论:使用生物膜的患者,唇腭向骨厚度及密度的增加均优于未使用生物膜的患者。在上前牙区骨量不足患者的种植术中,可推荐使用MGBR技术。

PURPOSE：The purpose of this study was to investigate the effect of Bio-Gide in MGBR（membrane guided bone regeneration） in the anterior maxilla dental implant therapy.METHODS：Fifty five cases underwent dental implant therapy in the anterior maxilla with insufficient maxillary anterior bone,including 29 patients with embedded 40 implants using MGBR and 26 patients with embedded 40 implants without using MGBR.The condition of bone around implant before implantation and before final restoration was observed and recorded.The thickness of the bone was measured with vernier caliper,the density and the bone loss were determined by X-ray examination.The results were analyzed with X-ray radiographs image analysis system（Sidexis） and SPSS16.0 software package.RESULTS：Univariate analysis showed that there was significant difference in the thickness and the density of the bone between before implant operation and before restoration（P0.05）.There was significant difference between the thickness and the density of the bone between with and without MGBR（P0.05）.CONCLUSIONS：These results suggest that the thickness and the density of the bone in the group with MGBR is better than the group without MGBR.It is recommended to use MGBR in dental implant therapy in the anterior maxilla with insufficient bone.