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抗癫痫药血药浓度测定中样本保存稳定性的考察

Investigate stability of sample storage in antieptics plasma sample determined by FPIA
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摘要 目的实验4℃冰箱冷藏保存下,丙戊酸钠和卡马西平血药浓度一周的稳定性。方法采用荧光偏振免疫法TDx对丙戊酸钠和卡马西平一周内的血药浓度测定。结果一周内的丙戊酸钠血药浓度RSD%为3.82,1.31,2.89,卡马西平一周内的血药浓度RSD%为2.89,2.99,2.32。结论4℃冷藏环境下,丙戊酸钠和卡马西平的血药浓度在一周内是稳定的。 OBJECTIVE the experiment is about the stability of the concentration of carbanmazepine and Valproic acid in serum which is stored in refrigerator under 4℃ for a week. METHODS determine the concentration of carbanmazepine and Valproic acid in serum for a week by FPIA. RESULTS the RSD% of the concentration of carbanmazepine in serum for a week is 3.82,1.31,2.89 , the RSD% of the concentration of Valproic acid in serum for a week is 2.89,2.99,2.32. CONCLUSIONS the concentration of carbanmazepine and Valproie acid in serum under 4 ℃ environment for a week is stability.
出处 《中国中医药咨讯》 2010年第36期3-5,共3页
关键词 血药浓度监测 荧光免疫偏振法 卡马西乎 丙戊酸钠 FPIA TDM earbanmazepine Valproic acid
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