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白三烯支气管激发试验及其临床意义 被引量:4

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摘要 半胱氨酰白三烯(简称白三烯,LT)是支气管哮喘(简称哮喘)炎症形成的重要介质,能够遏制白三烯炎症通路的白三烯受体拮抗剂,已被用于控制哮喘发作,但临床上发现部分患者的疗效不够理想.如何认识白三烯在气道炎症发展中的作用?使用白三烯作为激发剂进行支气管激发试验,能否更特异地衡量气道炎症,能否客观地评价白三烯受体拮抗剂(LTRA)的疗效,从而在本质上探索白三烯与哮喘的关系?现将国内外有关研究结果综述如下.
出处 《中华结核和呼吸杂志》 CAS CSCD 北大核心 2011年第1期54-56,共3页 Chinese Journal of Tuberculosis and Respiratory Diseases
基金 广东省自然科学基金(9152800001000019)
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