摘要
目的探讨医院临床分离的肺炎克雷伯菌(KPN)耐药现状,为临床医师合理用药提供试验依据。方法采用回顾性调查的方法对136株KPN的耐药性进行分析。结果临床送检的痰液、分泌物和尿液的标本分离的KPN占全部的86.0%,其中痰液标本分离出的菌株数最多,占64.7%;KPN产超广谱β-内酰胺酶(ESBLs)阳性率为42.6%,切有逐年上升的趋势;KPN对亚胺培南/西司他丁99.3%敏感,对氨苄西林耐药率最高,达96.3%。结论 KPN的耐药性已十分严重,应经加强监测、预防与控制。
OBJECTIVE To approach the drug resistance of clinically isolated Klebsiella pneumoniae （KPN） , to provide the scientific accordance for the reasonable application of the antibiotics. METHODS Rerospective investigation method was applied to analyze the drug resistance of 136 strains of K. pneumoniae. RESULTS The detection rate of the extended spectrum β-1actamases （ESBLs）-producing KPN was 42.6 %. KPN was sensitive to imipenem with the drug sensitivity rate of 99. 30%. And which to ampicillin was the highest with 96. 3%. CONCLUSION The drug resistance status of KPN is very serious. Hospital should strengthen the monitoring, prevention and control of it.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第1期154-155,共2页
Chinese Journal of Nosocomiology
关键词
医院感染
肺炎克雷伯菌
产超广谱Β-内酰胺酶
耐药性
Nosocomial infection
Klebsiella pneumoniae
Extended spectrum β-lactamases
Drug resistance
